A meta-analysis of randomized controlled trials shows no evidence that periodontal treatment during pregnancy prevents adverse pregnancy outcomes Critical Summary Prepared by: Lorena Baccaglini DDS, DDS, MS, PhD 

A Critical Summary of:

Obstetric outcomes after treatment of periodontal disease during pregnancy: systematic review and meta-analysis

Polyzos, N. P., Polyzos, I. P., Zavos, A., Valachis, A., Mauri, D., Papanikolaou, E. G., Tzioras, S., Weber, D., Messinis, I. E.. BMJ. 2010;341():c7017

Published Date: 9/30/2011

This summary is published in the Journal of the American Dental Association and can be accessed at :-


  • Systematic Review Conclusion:

    Treatment of periodontal disease with scaling and root planing (SRP) during pregnancy is unlikely to reduce the risk of preterm birth or low birth weight.

  • Critical Summary Assessment:

    A meta-analysis of 11 randomized controlled trials, including recently published high-quality studies, showed no evidence that SRP during pregnancy prevents preterm birth or other adverse pregnancy outcomes.

  • Evidence Quality Rating:


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