Pain after routine endodontic therapy may not have originated from the treated tooth Critical Summary Prepared by: Paul Benjamin DMD 

A Critical Summary of:

Frequency of nonodontogenic pain after endodontic therapy: a systematic review and meta-analysis

Nixdorf, D. R., Moana-Filho, E. J., Law, A. S., McGuire, L. A., Hodges, J. S., John, M. T.. Journal of Endodontics. 2010;36(9):1494-8

Published Date: 12/5/2011

This summary is published in the Journal of the American Dental Association and can be accessed at :-


  • Systematic Review Conclusion:

    The reviewers estimate that the frequency of nonodontogenic pain after endodontic therapy is 3.4 percent.

  • Critical Summary Assessment:

    An appropriately designed systematic review demonstrated that more than one-half of all cases of persistent pain may be of nonodontogenic origin.

  • Evidence Quality Rating:


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