Articaine is superior to lidocaine in providing pulpal anesthesia Critical Summary Prepared by: L. Virginia Powell DMD, GPR 

A Critical Summary of:

The pulpal anesthetic efficacy of articaine versus lidocaine in dentistry: a meta-analysis

Brandt, R. G., Anderson, P. F., McDonald, N. J., Sohn, W., Peters, M. C.. Journal of the American Dental Association. 2011;142(5):493-504

Published Date: 8/2/2012

This summary is published in the Journal of the American Dental Association and can be accessed at :-


  • Systematic Review Conclusion:

    Articaine provides a higher rate of anesthetic success in anesthetizing pulpal tissues than does lidocaine, although the method of administration used and the patient’s pulpal status may diminish this effect.

  • Critical Summary Assessment:

    Data from a randomized clinical trial provided evidence of the superior anesthetic qualities of 4 percent articaine compared with those of 2 percent lidocaine, although the difference possibly could be less evident if the teeth are inflamed or the method of delivery is by means of block injection.

  • Evidence Quality Rating:


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