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Non-fluoride agents for caries prevention (2011)

A panel of experts convened by the American Dental Association (ADA) Council on Scientific Affairs presents evidence-based clinical practice guideline and systematic review on non-fluoride agents for caries prevention including sucrose-free polyol chewing gums, xylitol dentifrices, chlorhexidine, chlorhexidine in combination with thymol, calcium-containing agents, phosphate containing agents, casein derivatives, sialogogues, iodine and triclosan. The panel concluded that certain non-fluoride agents may provide some benefit as adjunctive therapies in children and adults at higher risk of developing either root or coronal caries. As part of the evidence-based approach to care, these clinical recommendations should be integrated with the practitioner’s professional judgment and the patient’s needs and preferences.

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