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Associated Topics

Evidence indicates minimal short-term space loss after premature loss of primary first molars

Greg Huang DMD, MSD, MPH; Jacob DaBell DDS .


Systematic Review Conclusion

The reported magnitude of space loss after premature loss of primary first molars—1.5 millimeters per arch side in the mandible and 1.0 mm per arch side in the maxilla—is not likely to be of clinical significance in most cases.

Critical Summary Assessment

The reviewers’ conclusion was made on the basis of the results of only three studies, which included a total of 70 patients who were followed by investigators for up to eight months.

Evidence Quality Rating

Limited Evidence

This summary is published in the Journal of the American Dental Association and can be accessed at:

Critical Summary Publication Date:


These summaries are not intended to, and do not, express, imply, or summarize standards of care, but rather provide a concise reference for dentists to aid in understanding and applying evidence from the referenced systematic review in making clinically sound decisions as guided by their clinical judgment and by patient needs. American Dental Association © 2019