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Glass ionomer cement and resin-based fissure sealants are equally effective in caries prevention.

Sachin Seth DDS .


Systematic Review Conclusion

The evidence suggests that there is no difference in the caries-preventive effects of glass ionomer cement (GIC) and resin-based fissure sealants. Therefore, both materials appear to be equally suitable for clinical application as fissure sealant materials.

Critical Summary Assessment

The results of a systematic review of limited evidence showed that there is no difference between the use of GIC and resin-based fissure sealants on permanent teeth in the prevention of dental caries. The conclusion that both sealant materials are equally effective does not reflect the possible confounding effects of either the resin-based fissure sealant or the GIC fissure sealant used in a split-mouth design.

Evidence Quality Rating

Limited Evidence

This summary is published in the Journal of the American Dental Association and can be accessed at:

Critical Summary Publication Date:


These summaries are not intended to, and do not, express, imply, or summarize standards of care, but rather provide a concise reference for dentists to aid in understanding and applying evidence from the referenced systematic review in making clinically sound decisions as guided by their clinical judgment and by patient needs. American Dental Association © 2019