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Articaine is superior to lidocaine in providing pulpal anesthesia

L. Virginia Powell DMD, GPR .


Systematic Review Conclusion

Articaine provides a higher rate of anesthetic success in anesthetizing pulpal tissues than does lidocaine, although the method of administration used and the patient’s pulpal status may diminish this effect.

Critical Summary Assessment

Data from a randomized clinical trial provided evidence of the superior anesthetic qualities of 4 percent articaine compared with those of 2 percent lidocaine, although the difference possibly could be less evident if the teeth are inflamed or the method of delivery is by means of block injection.

Evidence Quality Rating

Good Evidence

This summary is published in the Journal of the American Dental Association and can be accessed at:

Critical Summary Publication Date:


These summaries are not intended to, and do not, express, imply, or summarize standards of care, but rather provide a concise reference for dentists to aid in understanding and applying evidence from the referenced systematic review in making clinically sound decisions as guided by their clinical judgment and by patient needs. American Dental Association © 2019