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Effectiveness of non-conventional methods for accelerated orthodontic tooth movement: a systematic review and meta-analysis

Gkantidis, N., Mistakidis, I., Kouskoura, T., Pandis, N. . J Dent. 2014;42(10):1300-19

OBJECTIVES: To assess the available evidence on the effectiveness of accelerated orthodontic tooth movement through surgical and non-surgical approaches in orthodontic patients. METHODS: Randomized controlled trials and controlled clinical trials were identified through electronic and hand searches (last update: March 2014). Orthognathic surgery, distraction osteogenesis, and pharmacological approaches were excluded. Risk of bias was assessed using the Cochrane risk of bias tool. RESULTS: Eighteen trials involving 354 participants were included for qualitative and quantitative synthesis. Eight trials reported on low-intensity laser, one on photobiomodulation, one on pulsed electromagnetic fields, seven on corticotomy, and one on interseptal bone reduction. Two studies on corticotomy and two on low-intensity laser, which had low or unclear risk of bias, were mathematically combined using the random effects model. Higher canine retraction rate was evident with corticotomy during the first month of therapy (WMD=0.73; 95% CI: 0.28, 1.19, p

Inconclusive evidence for the effectiveness of nonconventional methods in accelerating orthodontic tooth movement

Abdulraheem Alwafi, BDS .


Systematic Review Conclusion

A moderate level of evidence exists regarding low-intensity laser therapy and a low level of evidence exists regarding corticotomy regarding effectiveness in acceleration of orthodontic tooth movement. As for interseptal bone reduction, photobiomodulation, or pulsed electromagnetic fields, the evidence level is limited.

Critical Summary Assessment

Low-intensity laser therapy and corticotomy may be effective for accelerating orthodontic tooth movement, although their real clinical effect is questionable.

Evidence Quality Rating

Limited Evidence

This summary is published in the Journal of the American Dental Association and can be accessed at:

Critical Summary Publication Date:


These summaries are not intended to, and do not, express, imply, or summarize standards of care, but rather provide a concise reference for dentists to aid in understanding and applying evidence from the referenced systematic review in making clinically sound decisions as guided by their clinical judgment and by patient needs. American Dental Association © 2019