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Platelet-rich fibrin membrane does not improve clinical outcomes compared with other treatment modalities in the treatment of gingival recession

Yumi Ogata, DDS, DMD, MS, DDS, DMD, MS Yumi Ogata, Yong Hur, DDS, DMD, MS .


Systematic Review Conclusion

The use of platelet-rich fibrin (PRF) membrane did not improve clinical outcomes (root coverage [RC], clinical attachment level [CAL], and keratinized mucosa width [KMW]) compared with other treatment modalities in Miller Class I and II gingival recession.

Critical Summary Assessment

The results of this well-conducted systematic review show limited evidence on the effects of PRF membrane on the clinical outcomes in the treatment of gingival recession, for which there are no clinical advantages of PRF membranes over other treatment modalities. However, the clinical significance of the added benefits is unclear due to the lack of patient-oriented outcome measures.

Evidence Quality Rating

Limited Evidence

This summary is published in the Journal of the American Dental Association and can be accessed at:

Critical Summary Publication Date:


These summaries are not intended to, and do not, express, imply, or summarize standards of care, but rather provide a concise reference for dentists to aid in understanding and applying evidence from the referenced systematic review in making clinically sound decisions as guided by their clinical judgment and by patient needs. American Dental Association © 2019