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Non-fluoride Caries Preventive Agents (2011)

A panel of experts convened by the American Dental Association (ADA) Council on Scientific Affairs presents evidence-based clinical practice guideline and systematic review on non-fluoride agents for caries prevention including sucrose-free polyol chewing gums, xylitol dentifrices, chlorhexidine, chlorhexidine in combination with thymol, calcium-containing agents, phosphate containing agents, casein derivatives, sialogogues, iodine and triclosan. The panel concluded that certain non-fluoride agents may provide some benefit as adjunctive therapies in children and adults at higher risk of developing either root or coronal caries. As part of the evidence-based approach to care, these clinical recommendations should be integrated with the practitioner’s professional judgment and the patient’s needs and preferences.

An update of this guideline is expected in 2021.

Clinical Recommendations 

Chairside Guide